Syntaxin 3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Syntaxin 3, also known as STX3, is a protein[5] which in humans is encoded by the STX3 gene.[6][7]

AliasesSTX3, STX3A, Syntaxin 3, MVID2, RDMVID, DIAR12
End59,805,882 bp[1]
Quick facts STX3, Identifiers ...
STX3
Identifiers
AliasesSTX3, STX3A, Syntaxin 3, MVID2, RDMVID, DIAR12
External IDsOMIM: 600876; MGI: 103077; HomoloGene: 80191; GeneCards: STX3; OMA:STX3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001178040
NM_004177

RefSeq (protein)

NP_001171511
NP_004168

NP_001020478
NP_001273472
NP_035632
NP_689344
NP_001347315

Location (UCSC)Chr 11: 59.71 – 59.81 MbChr 19: 11.75 – 11.8 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is a member of the syntaxin family of cellular receptors for transport vesicles which participate in exocytosis in neutrophils.[6] STX3 has an important role in the growth of neurites and serves as a direct target for omega-6 arachidonic acid.[8] Mutations in Syntaxin 3 cause Microvillus inclusion disease.[9]

Interactions

Syntaxin 3 has been shown to interact with SNAP-25,[10][11][12] SNAP23[11][12][13][14] and SNAP29.[12]

References

Further reading

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