T-complex 1

TCP1
Identifiers
Aliases	TCP1, CCT-alpha, CCT1, CCTa, D6S230E, TCP-1-alpha, T-complex 1
External IDs	OMIM: 186980; MGI: 98535; HomoloGene: 5656; GeneCards: TCP1; OMA:TCP1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	159,789,703 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	13,143,954 bp
RNA expression pattern
	Top expressed in
	gonad; ; ganglionic eminence; ; left testis; ; right testis; ; ventricular zone; ; left ovary; ; gastric mucosa; ; right ovary; ; body of pancreas; ; skin of abdomen;
	Top expressed in
	spermatid; ; spermatocyte; ; testicle; ; lens; ; genital tubercle; ; epiblast; ; tail of embryo; ; neural tube; ; mesencephalon; ; ventricular zone;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; ATP binding; ubiquitin protein ligase binding; protein folding chaperone activity; unfolded protein binding; RNA binding;
Cellular component	cytoplasm; cell body; cytosol; centrosome; Golgi apparatus; pericentriolar material; myelin sheath; microtubule organizing center; zona pellucida receptor complex; heterochromatin; acrosomal vesicle; chaperonin-containing T-complex; microtubule; extracellular exosome; cytoskeleton;
Biological process	tubulin complex assembly; positive regulation of protein localization to Cajal body; positive regulation of establishment of protein localization to telomere; scaRNA localization to Cajal body; regulation of macrophage apoptotic process; protein stabilization; positive regulation of telomere maintenance via telomerase; toxin transport; protein folding; positive regulation of telomerase activity; translocation of peptides or proteins into host cell cytoplasm; positive regulation of telomerase RNA localization to Cajal body; binding of sperm to zona pellucida; 'de novo' protein folding; chaperone-mediated protein folding; interleukin-12-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	6950
	21454
	ENSG00000120438
	ENSMUSG00000068039
	P17987
	P11983
	NM_030752; NM_001008897
	NM_001290712; NM_013686
	NP_001008897; NP_110379
	NP_001277641; NP_038714
	Wikidata
View/Edit Human	View/Edit Mouse

T-complex protein 1 or T-complex protein 1 subunit alpha, abbreviated TCP1 or TCP-1,^[a] is a protein that in humans is encoded by the TCP1 gene.^[5]^[6]^[7]