TCEA2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Transcription elongation factor A protein 2 is a protein that in humans is encoded by the TCEA2 gene.[5][6][7]

PDBOrtholog search: PDBe RCSB
AliasesTCEA2, TFIIS, transcription elongation factor A2
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TCEA2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTCEA2, TFIIS, transcription elongation factor A2
External IDsOMIM: 604784; MGI: 107368; HomoloGene: 68304; GeneCards: TCEA2; OMA:TCEA2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003195
NM_198723

NM_009326
NM_001356342
NM_001356343

RefSeq (protein)

NP_003186
NP_942016
NP_003186.1

NP_033352
NP_001343271
NP_001343272

Location (UCSC)Chr 20: 64.05 – 64.07 MbChr 2: 181.32 – 181.33 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene.[7]

Interactions

TCEA2 has been shown to interact with MAGEA11.[8]

References

Further reading

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