TESK1
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Dual specificity testis-specific protein kinase 1 is an enzyme that in humans is encoded by the TESK1 gene.[4][5]
External IDsOMIM: 601782; MGI: 1201675; HomoloGene: 4577; GeneCards: TESK1; OMA:TESK1 - orthologs
Function
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis.[5]
