THAP1

THAP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2JTG, 2KO0, 2L1G
Identifiers
Aliases	THAP1, DYT6, THAP domain containing, apoptosis associated protein 1, THAP domain containing 1
External IDs	OMIM: 609520; MGI: 1921004; HomoloGene: 10005; GeneCards: THAP1; OMA:THAP1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	42,843,325 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	26,654,179 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; gonad; ; testicle; ; muscle of thigh; ; Achilles tendon; ; buccal mucosa cell; ; Epithelium of choroid plexus; ; monocyte; ; gastrocnemius muscle; ; ganglionic eminence;
	Top expressed in
	primary oocyte; ; spermatocyte; ; interventricular septum; ; secondary oocyte; ; otolith organ; ; zygote; ; trigeminal ganglion; ; utricle; ; otic vesicle; ; hand;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; sequence-specific DNA binding; DNA binding; zinc ion binding; protein binding; identical protein binding; nucleic acid binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein homodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	PML body; intracellular membrane-bounded organelle; nucleus; nucleoplasm; fibrillar center;
Biological process	cell cycle; endothelial cell proliferation; regulation of mitotic cell cycle; transcription, DNA-templated; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	55145
	73754
	ENSG00000131931
	ENSMUSG00000037214
	Q9NVV9
	Q8CHW1
	NM_199003; NM_018105
	NM_199042
	NP_060575; NP_945354
	NP_950243
	Wikidata
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