TIMM10

Mitochondrial import inner membrane translocase subunit Tim10 is an enzyme that in humans is encoded by the TIMM10 gene.^[5][6]

PDBOrtholog search: PDBe RCSB

AliasesTIMM10, TIM10, TIM10A, translocase of inner mitochondrial membrane 10 homolog (yeast), translocase of inner mitochondrial membrane 10, TIMM10A

External IDsOMIM: 602251; MGI: 1353429; HomoloGene: 40845; GeneCards: TIMM10; OMA:TIMM10 - orthologs

Chr.Chromosome 11 (human)^[1]

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TIMM10
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2BSK
Identifiers
Aliases	TIMM10, TIM10, TIM10A, translocase of inner mitochondrial membrane 10 homolog (yeast), translocase of inner mitochondrial membrane 10, TIMM10A
External IDs	OMIM: 602251; MGI: 1353429; HomoloGene: 40845; GeneCards: TIMM10; OMA:TIMM10 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q12.1 Start 57,528,464 bp[1] End 57,530,803 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 D Start 84,657,341 bp[2] End 84,660,557 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gingival epithelium prefrontal cortex muscle of thigh islet of Langerhans gastrocnemius muscle anterior cingulate cortex apex of heart tendon of biceps brachii right lobe of liver biceps brachii Top expressed in facial motor nucleus myocardium of ventricle right ventricle morula endocardial cushion atrioventricular valve digastric muscle embryo soleus muscle cardiac muscles More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding chaperone binding protein binding protein homodimerization activity metal ion binding transporter activity Cellular component mitochondrial inner membrane mitochondrial intermembrane space TIM23 mitochondrial import inner membrane translocase complex mitochondrial intermembrane space protein transporter complex membrane mitochondrion TIM22 mitochondrial import inner membrane insertion complex Biological process protein transport protein insertion into mitochondrial inner membrane protein targeting to mitochondrion hearing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26519 30059 Ensembl ENSG00000134809 ENSMUSG00000027076 UniProt P62072 P62073 RefSeq (mRNA) NM_012456 NM_013899 RefSeq (protein) NP_036588 NP_038927 Location (UCSC) Chr 11: 57.53 – 57.53 Mb Chr 2: 84.66 – 84.66 Mb PubMed search [3] [4]
Wikidata
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TIMM10 belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM]^[6]