TINF2

TINF2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3BQO, 3BU8
Identifiers
Aliases	TINF2, DKCA3, TIN2, TERF1 interacting nuclear factor 2
External IDs	OMIM: 604319; MGI: 107246; HomoloGene: 8264; GeneCards: TINF2; OMA:TINF2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	24,242,674 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,919,277 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; right adrenal gland; ; right adrenal cortex; ; left adrenal gland; ; monocyte; ; left adrenal cortex; ; bone marrow cell; ; blood; ; tonsil; ; spleen;
	Top expressed in
	primary oocyte; ; secondary oocyte; ; primitive streak; ; zygote; ; epiblast; ; seminiferous tubule; ; spermatocyte; ; tail of embryo; ; granulocyte; ; somite;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; telomeric DNA binding; protein binding;
Cellular component	nuclear telomere cap complex; nuclear matrix; perinucleolar chromocenter; nucleoplasm; chromosome; shelterin complex; telomere; nucleus; nuclear body;
Biological process	protein localization to chromosome, telomeric region; negative regulation of epithelial cell proliferation; telomere assembly; negative regulation of protein ADP-ribosylation; telomere capping; negative regulation of telomere maintenance via telomerase; regulation of telomere maintenance via telomere lengthening;
	Sources:Amigo / QuickGO
Orthologs
	26277
	28113
	ENSG00000092330; ENSG00000284915
	ENSMUSG00000007589
	Q9BSI4
	Q9QXG9; Q8K1K3
	NM_001099274; NM_012461; NM_001363668
	NM_145705
	NP_001092744; NP_036593; NP_001350597
	NP_663751
	Wikidata
View/Edit Human	View/Edit Mouse

TERF1-interacting nuclear factor 2 is a protein that in humans is encoded by the TINF2 gene.^[5]^[6] TINF2 is a component of the shelterin protein complex found at the end of telomeres.^[7]