TLK1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Serine/threonine-protein kinase tousled-like 1 is an enzyme that in humans is encoded by the TLK1 gene.[5][6][7]

AliasesTLK1, PKU-beta, tousled like kinase 1
End171,231,314 bp[1]
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TLK1
Identifiers
AliasesTLK1, PKU-beta, tousled like kinase 1
External IDsOMIM: 608438; MGI: 2441683; HomoloGene: 130657; GeneCards: TLK1; OMA:TLK1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001136554
NM_001136555
NM_012290

NM_172664
NM_001362963

RefSeq (protein)

NP_001130026
NP_001130027
NP_036422

NP_766252
NP_001349892

Location (UCSC)Chr 2: 170.99 – 171.23 MbChr 2: 70.54 – 70.66 Mb
PubMed search[3][4]
Wikidata
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Function

The Tousled-like kinases, first described in Arabidopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly.[supplied by OMIM][7]

Interactions

TLK1 has been shown to interact with ASF1B,[8][9] ASF1A[8][10] and TLK2.[11]

References

Further reading

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