TMBIM1

Transmembrane BAX inhibitor motif-containing protein 1 is a protein that in humans is encoded by the TMBIM1 gene.^[5][6]

AliasesTMBIM1, LFG3, MST100, MSTP100, RECS1, PP1201, transmembrane BAX inhibitor motif containing 1

External IDsOMIM: 610364; MGI: 1916910; HomoloGene: 36404; GeneCards: TMBIM1; OMA:TMBIM1 - orthologs

Chr.Chromosome 2 (human)^[1]

End218,292,586 bp^[1]

Quick facts Identifiers, Aliases ...

TMBIM1
Identifiers
Aliases	TMBIM1, LFG3, MST100, MSTP100, RECS1, PP1201, transmembrane BAX inhibitor motif containing 1
External IDs	OMIM: 610364; MGI: 1916910; HomoloGene: 36404; GeneCards: TMBIM1; OMA:TMBIM1 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q35 Start 218,274,197 bp[1] End 218,292,586 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 C3 Start 74,327,406 bp[2] End 74,344,781 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Descending thoracic aorta ascending aorta body of pancreas body of stomach gastric mucosa right lung gallbladder skin of leg skin of abdomen popliteal artery Top expressed in epithelium of stomach pyloric antrum vestibular membrane of cochlear duct left colon ankle mucous cell of stomach ascending aorta aortic valve carotid body transitional epithelium of urinary bladder More reference expression data BioGPS More reference expression data
Gene ontology Molecular function death receptor binding Cellular component integral component of membrane lysosomal membrane endosome Golgi apparatus lysosome endosome membrane extracellular exosome membrane plasma membrane specific granule membrane intracellular membrane-bounded organelle Biological process negative regulation of Fas signaling pathway positive regulation of blood vessel remodeling negative regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of catalytic activity neutrophil degranulation negative regulation of protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64114 69660 Ensembl ENSG00000135926 ENSMUSG00000006301 UniProt Q969X1 Q8BJZ3 RefSeq (mRNA) NM_022152 NM_001321427 NM_001321428 NM_001321429 NM_001321430 NM_001321432 NM_001321433 NM_001321435 NM_001321436 NM_001321438 NM_027154 RefSeq (protein) NP_001308356 NP_001308357 NP_001308358 NP_001308359 NP_001308361 NP_001308362 NP_001308364 NP_001308365 NP_001308367 NP_071435 NP_081430 Location (UCSC) Chr 2: 218.27 – 218.29 Mb Chr 1: 74.33 – 74.34 Mb PubMed search [3] [4]
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