TRIM11

Tripartite motif-containing protein 11 is a protein found in humans that is encoded by the TRIM11 gene.^[5][6]

AliasesTRIM11, BIA1, RNF92, tripartite motif containing 11

External IDsOMIM: 607868; MGI: 2137355; HomoloGene: 14225; GeneCards: TRIM11; OMA:TRIM11 - orthologs

Chr.Chromosome 1 (human)^[1]

End228,406,835 bp^[1]

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TRIM11
Identifiers
Aliases	TRIM11, BIA1, RNF92, tripartite motif containing 11
External IDs	OMIM: 607868; MGI: 2137355; HomoloGene: 14225; GeneCards: TRIM11; OMA:TRIM11 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q42.13 Start 228,393,673 bp[1] End 228,406,835 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B1.3 Start 58,868,919 bp[2] End 58,882,284 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar hemisphere right hemisphere of cerebellum granulocyte oocyte mucosa of transverse colon spleen mucosa of ileum blood cerebellar vermis monocyte Top expressed in granulocyte secondary oocyte spermatocyte zygote tibiofemoral joint corneal stroma thymus atrium primary oocyte lactiferous gland More reference expression data BioGPS n/a
Gene ontology Molecular function ubiquitin-protein transferase activity zinc ion binding transcription factor binding protein binding protein domain specific binding ubiquitin protein ligase activity metal ion binding transferase activity Cellular component cytoplasm intracellular anatomical structure nucleus cytosol Biological process negative regulation of neurogenesis innate immune response negative regulation of transcription, DNA-templated defense response to virus protein ubiquitination negative regulation of viral transcription negative regulation of viral entry into host cell positive regulation of viral entry into host cell Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81559 94091 Ensembl ENSG00000154370 ENSMUSG00000020455 UniProt Q96F44 Q99PQ2 RefSeq (mRNA) NM_145214 NM_001290988 NM_053168 RefSeq (protein) NP_660215 NP_001277917 NP_444398 Location (UCSC) Chr 1: 228.39 – 228.41 Mb Chr 11: 58.87 – 58.88 Mb PubMed search [3] [4]
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The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified.^[6]