TRIM29

Protein in humans From Wikipedia, the free encyclopedia

Tripartite motif-containing protein 29 is a protein that in humans is encoded by the TRIM29 gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesTRIM29, ATDC, tripartite motif containing 29
Quick facts Available structures, PDB ...
TRIM29
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTRIM29, ATDC, tripartite motif containing 29
External IDsOMIM: 610658; MGI: 1919419; HomoloGene: 8100; GeneCards: TRIM29; OMA:TRIM29 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012101
NM_058193
NM_001330382

NM_023655

RefSeq (protein)

NP_001317311
NP_036233

NP_076144

Location (UCSC)Chr 11: 120.11 – 120.19 MbChr 9: 43.22 – 43.25 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia–telangiectasia phenotype.[6]

Interactions

TRIM29 has been shown to interact with TRIM23[5] and GCC1.[7]

References

Further reading

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