TRIM45

tripartite motif containing 45, also known as TRIM45, is a human gene.^[5]

PDBOrtholog search: PDBe RCSB

AliasesTRIM45, RNF99, tripartite motif containing 45

External IDsOMIM: 609318; MGI: 1918187; HomoloGene: 11865; GeneCards: TRIM45; OMA:TRIM45 - orthologs

Chr.Chromosome 1 (human)^[1]

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TRIM45
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DS4
Identifiers
Aliases	TRIM45, RNF99, tripartite motif containing 45
External IDs	OMIM: 609318; MGI: 1918187; HomoloGene: 11865; GeneCards: TRIM45; OMA:TRIM45 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p13.1 Start 117,111,060 bp[1] End 117,122,587 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F2.2 Start 100,829,518 bp[2] End 100,844,236 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte right uterine tube apex of heart testicle muscle of thigh gastrocnemius muscle right auricle of heart gonad tibialis anterior muscle deltoid muscle Top expressed in otolith organ utricle vestibular sensory epithelium olfactory system olfactory epithelium seminiferous tubule internal carotid artery external carotid artery spermatid Jacobson's organ More reference expression data BioGPS n/a
Gene ontology Molecular function zinc ion binding metal ion binding Cellular component intracellular anatomical structure nucleus nucleoplasm intercellular bridge cytoplasm cytosol Biological process bone development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 80263 229644 Ensembl ENSG00000134253 ENSMUSG00000033233 UniProt Q9H8W5 Q6PFY8 RefSeq (mRNA) NM_001145635 NM_025188 NM_001165952 NM_001165953 NM_194343 RefSeq (protein) NP_001139107 NP_079464 NP_001159424 NP_001159425 NP_919324 Location (UCSC) Chr 1: 117.11 – 117.12 Mb Chr 3: 100.83 – 100.84 Mb PubMed search [3] [4]
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This gene encodes a member of the tripartite motif family. The encoded protein may function as a [transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described.^[5]