TRIT1

TRIT1
Identifiers
Aliases	TRIT1, IPT, MOD5, GRO1, IPPT, IPTase, hGRO1, tRNA isopentenyltransferase 1, COXPD35
External IDs	OMIM: 617840; MGI: 1914216; HomoloGene: 7010; GeneCards: TRIT1; OMA:TRIT1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	39,883,511 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	122,948,742 bp
RNA expression pattern
	Top expressed in
	oocyte; ; body of pancreas; ; skin of leg; ; vagina; ; skin of abdomen; ; right uterine tube; ; secondary oocyte; ; left lobe of thyroid gland; ; prostate; ; body of uterus;
	Top expressed in
	saccule; ; medullary collecting duct; ; otic vesicle; ; renal corpuscle; ; otic placode; ; lacrimal gland; ; hair follicle; ; cumulus cell; ; primary oocyte; ; fossa;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; ATP binding; metal ion binding; tRNA dimethylallyltransferase activity; nucleic acid binding; zinc ion binding;
Cellular component	cytoplasm; mitochondrial matrix; mitochondrion; cellular component;
Biological process	mitochondrial tRNA modification; tRNA processing; tRNA modification;
	Sources:Amigo / QuickGO
Orthologs
	54802
	66966
	ENSG00000043514
	ENSMUSG00000028653
	Q9H3H1
	Q80UN9
	NM_001312691; NM_001312692; NM_017646
	NM_025873
	NP_001299620; NP_001299621; NP_060116
	NP_080149
	Wikidata
View/Edit Human	View/Edit Mouse

tRNA dimethylallyltransferase is an enzyme that in humans is encoded by the TRIT1 gene.

AliasesTRIT1, IPT, MOD5, GRO1, IPPT, IPTase, hGRO1, tRNA isopentenyltransferase 1, COXPD35

End39,883,511 bp^[1]

Quick facts Identifiers, Aliases ...

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It catalyzes the addition of an isopentenyl group from dimethylallyl diphosphate (DMAPP) onto adenosine residue 37 of certain tRNA molecules.^[5]^[6]^[7]

References