TRNT1

TRNT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1OU5, 4X4W
Identifiers
Aliases	TRNT1, CCA1, MtCCA, CGI-47, SIFD, tRNA nucleotidyl transferase 1, RPEM
External IDs	OMIM: 612907; MGI: 1917297; HomoloGene: 9333; GeneCards: TRNT1; OMA:TRNT1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	3,150,879 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	106,759,435 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; secondary oocyte; ; gonad; ; Achilles tendon; ; parietal pleura; ; epithelium of colon; ; pancreatic epithelial cell; ; cartilage tissue; ; metanephros; ; testicle;
	Top expressed in
	spermatocyte; ; zygote; ; spermatid; ; genital tubercle; ; secondary oocyte; ; tail of embryo; ; yolk sac; ; ventricular zone; ; embryo; ; atrioventricular valve;
	More reference expression data
	n/a
Gene ontology
Molecular function	CTP:3'-cytidine-tRNA cytidylyltransferase activity; transferase activity; nucleotide binding; tRNA binding; nucleotidyltransferase activity; ATP binding; CTP:tRNA cytidylyltransferase activity; RNA binding; 5'-3' RNA polymerase activity; ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity;
Cellular component	mitochondrial matrix; intracellular anatomical structure; mitochondrion; nucleoplasm;
Biological process	RNA processing; tRNA 3'-terminal CCA addition; tRNA processing; tRNA 3'-end processing; mitochondrial tRNA 3'-end processing;
	Sources:Amigo / QuickGO
Orthologs
	51095
	70047
	ENSG00000072756
	ENSMUSG00000013736
	Q96Q11
	Q8K1J6
	NM_001302946; NM_016000; NM_182916
	NM_001242358; NM_001242360; NM_027296
	NP_001289875; NP_886552; NP_001354250; NP_001354251; NP_001354252
	NP_001229287; NP_001229289; NP_081572
	Wikidata
View/Edit Human	View/Edit Mouse

tRNA-nucleotidyltransferase 1, is an enzyme that in humans is encoded by the TRNT1 gene.^[5]^[6]^[7] This enzyme adds the nucleotide sequence CCA to the 3' end of tRNA, using ATP and CTP as substrates. The sequence creates the binding site for an amino acid.^[8]