TSPAN31

Tetraspanin-31 is a protein that in humans is encoded by the TSPAN31 gene.^[5]

AliasesTSPAN31, SAS, tetraspanin 31

External IDsOMIM: 181035; MGI: 1914375; HomoloGene: 4359; GeneCards: TSPAN31; OMA:TSPAN31 - orthologs

Chr.Chromosome 12 (human)^[1]

End57,750,219 bp^[1]

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TSPAN31
Identifiers
Aliases	TSPAN31, SAS, tetraspanin 31
External IDs	OMIM: 181035; MGI: 1914375; HomoloGene: 4359; GeneCards: TSPAN31; OMA:TSPAN31 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q14.1 Start 57,738,013 bp[1] End 57,750,219 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 D3 Start 126,903,149 bp[2] End 126,906,133 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell islet of Langerhans pericardium right lobe of thyroid gland right adrenal gland corpus epididymis endothelial cell right adrenal cortex renal medulla gallbladder Top expressed in left lobe of liver medullary collecting duct renal corpuscle calvaria cumulus cell medial ganglionic eminence molar vas deferens efferent ductule aortic valve More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 6302 67125 Ensembl ENSG00000135452 ENSMUSG00000006736 UniProt Q12999 Q9CQ88 RefSeq (mRNA) NM_005981 NM_001330168 NM_001330169 NM_025982 RefSeq (protein) NP_001317097 NP_001317098 NP_005972 NP_080258 Location (UCSC) Chr 12: 57.74 – 57.75 Mb Chr 10: 126.9 – 126.91 Mb PubMed search [3] [4]
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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma.^[5]