TSPY1

Testis-specific Y-encoded protein 1 is a protein that in humans is encoded by the TSPY1 gene.^[3]

AliasesTSPY1, CT78, DYS14, TSPY, pJA923, testis specific protein, Y-linked 1, testis specific protein Y-linked 1

External IDsOMIM: 480100; HomoloGene: 87844; GeneCards: TSPY1; OMA:TSPY1 - orthologs

Chr.Y chromosome (human)^[1]

End9,469,749 bp^[1]

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TSPY1
Identifiers
Aliases	TSPY1, CT78, DYS14, TSPY, pJA923, testis specific protein, Y-linked 1, testis specific protein Y-linked 1
External IDs	OMIM: 480100; HomoloGene: 87844; GeneCards: TSPY1; OMA:TSPY1 - orthologs
Gene location (Human) Chr. Y chromosome (human)[1] Band Yp11.2 Start 9,466,955 bp[1] End 9,469,749 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad right testis left testis n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding molecular function Cellular component cytoplasm nucleus cellular component Biological process multicellular organism development nucleosome assembly cell differentiation cell population proliferation sex differentiation spermatogenesis gonadal mesoderm development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7258 n/a Ensembl ENSG00000258992 n/a UniProt Q01534 n/a RefSeq (mRNA) NM_003308 NM_001197242 NM_001320964 n/a RefSeq (protein) NP_001184171 NP_001307893 NP_003299 n/a Location (UCSC) Chr Y: 9.47 – 9.47 Mb n/a PubMed search [2] n/a
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The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Approximately 35 copies of this gene are present in humans, but only a single, nonfunctional orthologous gene is found in mice. Two transcript variants encoding different isoforms have been found for this gene.^[4] The protein is strongly overexpressed in gonadoblastoma.^[5]