TXNDC5

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Thioredoxin domain-containing protein 5 is a protein that in humans is encoded by the TXNDC5 gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesTXNDC5, ENDOPDI, ERP46, HCC-2, PDIA15, STRF8, UNQ364, HCC2, thioredoxin domain containing 5
Quick facts Available structures, PDB ...
TXNDC5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTXNDC5, ENDOPDI, ERP46, HCC-2, PDIA15, STRF8, UNQ364, HCC2, thioredoxin domain containing 5
External IDsOMIM: 616412; MGI: 2145316; HomoloGene: 11125; GeneCards: TXNDC5; OMA:TXNDC5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030810
NM_001145549
NM_022085

NM_001289598
NM_001289599
NM_145367

RefSeq (protein)

NP_001139021
NP_110437

NP_001276527
NP_001276528
NP_663342

Location (UCSC)Chr 6: 7.88 – 7.91 MbChr 13: 38.68 – 38.71 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a protein disulfide-isomerase.[6] Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. This gene can be co-transcribed with the upstream gene MUTED.[5]

References

Further reading

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