Thyronamine
Chemical compound
From Wikipedia, the free encyclopedia
Thyronamine is a type of decarboxylated and deiodinated metabolite of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3). The word thyronamine can refer to either the family of molecules, or the specific molecule from which they are derived.
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| Names | |
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| Preferred IUPAC name
4-[4-(2-Aminoethyl)phenoxy]phenol | |
| Identifiers | |
3D model (JSmol) |
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| ChEMBL | |
| ChemSpider | |
| MeSH | thyronamine |
PubChem CID |
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CompTox Dashboard (EPA) |
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| Properties | |
| C14H15NO2 | |
| Molar mass | 229.279 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Types
The group includes:
- Thyronamine (T0AM)
- 3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), an intracellular G protein-coupled receptor[1]
- 3,5-Diiodothyronamine (T2AM)
- 3,5,3'-Triiodothyronamine (T3AM)