Toltrazuril
Chemical compound
From Wikipedia, the free encyclopedia
Toltrazuril is an antiparasitic medication used primarily to treat coccidiosis in animals. Coccidiosis is a parasitic disease caused by coccidia, which are microscopic, spore-forming, single-celled obligate intracellular parasites belonging to the apicomplexan class Conoidasida.[1][2][3]
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| Trade names | Baycox, Tolcox |
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| ECHA InfoCard | 100.132.547 |
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| Formula | C18H14F3N3O4S |
| Molar mass | 425.38 g·mol−1 |
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Mechanism of action
Toltrazuril works by interfering with the protozoa's ability to reproduce. It disrupts the division of the protozoal nucleus and damages the cell membrane of the parasites. This action results in the destruction of the coccidia at all stages of their life cycle.[4]
Use in veterinary medicine
Toltrazuril is widely used in veterinary medicine to treat coccidiosis in various animals, including poultry, pigs, cattle, sheep, and companion animals like dogs and cats. It is often administered as a single dose or in a series of doses depending on the severity of the infection and the species being treated.[5][6]