TOMM20

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Mitochondrial import receptor subunit TOM20 homolog is a protein that in humans is encoded by the TOMM20 gene.[5][6][7][8] TOM20 is one of the receptor systems of the translocase of the outer membrane (TOM) complex in the outer mitochondrial membrane.

PDBOrtholog search: PDBe RCSB
AliasesTOMM20, MAS20, MOM19, TOM20, translocase of outer mitochondrial membrane 20
Quick facts Available structures, PDB ...
TOMM20
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTOMM20, MAS20, MOM19, TOM20, translocase of outer mitochondrial membrane 20
External IDsOMIM: 601848; MGI: 1915202; HomoloGene: 44649; GeneCards: TOMM20; OMA:TOMM20 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014765

NM_024214

RefSeq (protein)

NP_055580
NP_055580.1

NP_077176

Location (UCSC)Chr 1: 235.11 – 235.13 MbChr 8: 127.66 – 127.67 Mb
PubMed search[3][4]
Wikidata
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Function

In mitochondrial protein import, TOM20 is closely associated with the pore-forming TOM40 complex and acts by recognizing and binding the N-terminal MTSs (matrix-targeting sequences), which form an amphipathic alpha helix and aid passage of the target proteins into the mitochondrial matrix.[9]

See also

References

Further reading

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