Trisescaline

Pharmaceutical compound From Wikipedia, the free encyclopedia

Trisescaline (TRIS), also known as trescaline or as 3,4,5-triethoxyphenethylamine, is a chemical compound of the phenethylamine and scaline families related to mescaline.[1][2][3][4] It is the derivative of mescaline in which the three methoxy groups on the phenyl ring have been replaced with ethoxy groups.[1][2][3][4]

Other namesTRIS; Trescaline; 3,4,5-Triethoxyphenethylamine
ATC code
  • None
Quick facts Clinical data, Other names ...
Trisescaline
Clinical data
Other namesTRIS; Trescaline; 3,4,5-Triethoxyphenethylamine
Routes of
administration
Oral[1]
ATC code
  • None
Pharmacokinetic data
Duration of actionUnknown[1]
Identifiers
  • 2-(3,4,5-triethoxyphenyl)ethan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H23NO3
Molar mass253.342 g·mol−1
3D model (JSmol)
  • CCOc1c(cc(cc1OCC)CCN)OCC
  • InChI=1S/C14H23NO3/c1-4-16-12-9-11(7-8-15)10-13(17-5-2)14(12)18-6-3/h9-10H,4-8,15H2,1-3H3 checkY
  • Key:ZIZQSXJSBRQJEB-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)
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In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists trisescaline's dose as greater than 240 mg orally and its duration as unknown.[1][2][3] The drug produced no effects at tested doses of up to 240 mg orally.[1]

Trisescaline produced no psychedelic-like behavioral effects in cats even at very high doses.[1]

The chemical synthesis of trisescaline has been described.[1][4]

Trisescaline was first described in the scientific literature by Shulgin and Peyton Jacob III in 1984.[4] Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.[1]

See also

References

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