Trisescaline
Pharmaceutical compound
From Wikipedia, the free encyclopedia
Trisescaline (TRIS), also known as trescaline or as 3,4,5-triethoxyphenethylamine, is a chemical compound of the phenethylamine and scaline families related to mescaline.[1][2][3][4] It is the derivative of mescaline in which the three methoxy groups on the phenyl ring have been replaced with ethoxy groups.[1][2][3][4]
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| Other names | TRIS; Trescaline; 3,4,5-Triethoxyphenethylamine |
| Routes of administration | Oral[1] |
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| Duration of action | Unknown[1] |
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| Formula | C14H23NO3 |
| Molar mass | 253.342 g·mol−1 |
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In his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists trisescaline's dose as greater than 240 mg orally and its duration as unknown.[1][2][3] The drug produced no effects at tested doses of up to 240 mg orally.[1]
Trisescaline produced no psychedelic-like behavioral effects in cats even at very high doses.[1]
The chemical synthesis of trisescaline has been described.[1][4]
Trisescaline was first described in the scientific literature by Shulgin and Peyton Jacob III in 1984.[4] Subsequently, it was described in greater detail by Shulgin in PiHKAL in 1991.[1]