Trofosfamide

Trofosfamide (INN) is a nitrogen mustard alkylating agent. It is sometimes abbreviated "TRO".^[1] It has been used in trials to study its effects on ependymoma, medulloblastoma, sarcoma, soft tissue,^{[clarification needed]} supratentorial PNET, and recurrent brain tumors.^[2]

Trade namesIxoten

AHFS/Drugs.comInternational Drug Names

Routes of
administrationBy mouth (film-coated tablets)

ATC code

• L01AA07 (WHO)

Quick facts Clinical data, Trade names ...

Trofosfamide

Clinical data
Trade names	Ixoten
AHFS/Drugs.com	International Drug Names
Routes of administration	By mouth (film-coated tablets)
ATC code	L01AA07 (WHO)
Legal status
Legal status	DE: § 48 AMG/§ 1 MPAV (Prescription only)
Identifiers
IUPAC name N,N,3-tris(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amide 2-oxide
CAS Number	22089-22-1 Y
PubChem CID	65702
ChemSpider	59129 N
UNII	H64JRU6GJ0
KEGG	D07252 Y
ChEMBL	ChEMBL462019 N
CompTox Dashboard (EPA)	DTXSID60865031
ECHA InfoCard	100.040.686
Chemical and physical data
Formula	C9H18Cl3N2O2P
Molar mass	323.58 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CN(P(=O)(OC1)N(CCCl)CCCl)CCCl
InChI InChI=1S/C9H18Cl3N2O2P/c10-2-6-13-5-1-9-16-17(13,15)14(7-3-11)8-4-12/h1-9H2 N Key:UMKFEPPTGMDVMI-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Close