Troleandomycin

Troleandomycin
Clinical data
AHFS/Drugs.com	Multum Consumer Information
MedlinePlus	a604026
ATC code	J01FA08 (WHO) ;
Identifiers
	IUPAC name (3R,5R,6R,7S,8R,11R,12S,13R,14S,15S)-12-[(4-O-acetyl-2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)oxy]-14-{[2-O-acetyl-3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-5,7,8,11,13,15-hexamethyl-4,10-dioxo-1,9-dioxaspiro[2.13]hexadec-6-yl acetate;
CAS Number	2751-09-9 ;
PubChem CID	5284630;
DrugBank	DB01361 ;
ChemSpider	4447675 ;
UNII	C4DZ64560D;
KEGG	D01322 ;
ChEBI	CHEBI:45735 ;
ChEMBL	ChEMBL564085 ;
PDB ligand	TAO (PDBe, RCSB PDB);
CompTox Dashboard (EPA)	DTXSID2023721 ;
ECHA InfoCard	100.018.539
Chemical and physical data
Formula	C41H67NO15
Molar mass	813.979 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O[C@@H]4[C@@H](N(C)C)C[C@H](O[C@H]4O[C@@H]3[C@H]([C@H](O[C@@H]1O[C@H]([C@H](OC(=O)C)[C@@H](OC)C1)C)[C@H](C(=O)O[C@H](C)[C@H](C)[C@H](OC(=O)C)[C@H](C(=O)[C@]2(OC2)C[C@@H]3C)C)C)C)C)C;
	InChI InChI=1S/C41H67NO15/c1-19-17-41(18-49-41)38(46)23(5)34(53-27(9)43)21(3)25(7)52-39(47)24(6)35(56-32-16-31(48-14)36(26(8)51-32)54-28(10)44)22(4)33(19)57-40-37(55-29(11)45)30(42(12)13)15-20(2)50-40/h19-26,30-37,40H,15-18H2,1-14H3/t19-,20+,21-,22+,23+,24+,25+,26-,30-,31-,32-,33-,34-,35-,36-,37+,40-,41-/m0/s1 ; Key:LQCLVBQBTUVCEQ-MCQAQMIOSA-N ;
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Troleandomycin (TAO for short^[1]) is a macrolide antibiotic. It was sold in Italy (branded Triocetin) and Turkey (branded Tekmisin). It is no longer sold in Italy as of 2018.^{[citation needed]}

AHFS/Drugs.comMultum Consumer Information

MedlinePlusa604026

ATC code

J01FA08 (WHO)

CAS Number

2751-09-9^Y

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The drug's mode of action is to bind to the ribosome, specifically in the tunnel through which the newly formed peptide egresses, thereby halting protein synthesis.^[2] Troleandomycin is a CYP3A4 inhibitor that may cause drug interactions.^{[citation needed]}

[1]

[2]

Troleandomycin

References

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