UNC84A

Protein unc-84 homolog A is a protein that in humans is encoded by the UNC84A gene.^[5][6]

AliasesSUN1, UNC84A, Sad1 and UNC84 domain containing 1

External IDsOMIM: 607723; MGI: 1924303; HomoloGene: 11544; GeneCards: SUN1; OMA:SUN1 - orthologs

Chr.Chromosome 7 (human)^[1]

End896,435 bp^[1]

Quick facts SUN1, Identifiers ...

SUN1
Identifiers
Aliases	SUN1, UNC84A, Sad1 and UNC84 domain containing 1
External IDs	OMIM: 607723; MGI: 1924303; HomoloGene: 11544; GeneCards: SUN1; OMA:SUN1 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p22.3 Start 816,615 bp[1] End 896,435 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G2 Start 139,186,392 bp[2] End 139,235,595 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte gastric mucosa mucosa of paranasal sinus right uterine tube body of uterus left ovary bronchial epithelial cell right hemisphere of cerebellum canal of the cervix right ovary Top expressed in spermatocyte spermatid saccule transitional epithelium of urinary bladder olfactory epithelium superior frontal gyrus ectoderm otic vesicle otic placode neural layer of retina More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding lamin binding protein-membrane adaptor activity Cellular component cytoplasm integral component of membrane nuclear inner membrane integral component of nuclear inner membrane nuclear membrane acrosomal membrane intracellular membrane-bounded organelle nucleus membrane meiotic nuclear membrane microtubule tethering complex nuclear envelope Biological process response to mechanical stimulus homologous chromosome pairing at meiosis nuclear envelope organization nuclear matrix anchoring at nuclear membrane ossification spermatogenesis nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration cell differentiation meiosis centrosome localization meiotic attachment of telomere to nuclear envelope Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23353 77053 Ensembl ENSG00000164828 ENSMUSG00000036817 UniProt O94901 Q9D666 RefSeq (mRNA) NM_025154 NM_001130965 NM_001171944 NM_001171945 NM_001171946 NM_001256115 NM_001256116 NM_001256117 NM_001256118 NM_024451 NM_001359494 NM_001359496 RefSeq (protein) NP_001124437 NP_001165415 NP_001165416 NP_001165417 NP_079430 NP_001354562 NP_001354563 NP_001354564 NP_001354565 NP_001354566 NP_001354567 NP_001354568 NP_001354569 NP_001354570 NP_001354571 NP_001354572 NP_001354573 NP_001354574 NP_001354575 NP_001354576 NP_001354577 NP_001354578 NP_001354580 NP_001354582 NP_001354584 NP_001354587 NP_001354589 NP_001354591 NP_001354593 NP_001354594 NP_001354595 NP_001354596 NP_001354597 NP_001354598 NP_001354599 NP_001354600 NP_001354601 NP_001354602 NP_001354603 NP_001354604 NP_001354605 NP_001354606 NP_001354607 NP_001354608 NP_001354609 NP_001354610 NP_001354611 NP_001354612 NP_001354613 NP_001354614 NP_001354615 NP_001354616 NP_001354617 NP_001354618 NP_001354619 NP_001354620 NP_001354621 NP_001354622 NP_001354623 NP_001354624 NP_001354625 NP_001354626 NP_001354627 NP_001354628 NP_001354629 NP_001354630 NP_001354631 NP_001354632 NP_001354633 NP_001354634 NP_001354635 NP_001354637 NP_001243044 NP_001243045 NP_001243046 NP_001243047 NP_077771 NP_001346423 NP_001346425 Location (UCSC) Chr 7: 0.82 – 0.9 Mb Chr 5: 139.19 – 139.24 Mb PubMed search [3] [4]
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This gene is a member of the unc-84 homolog family and encodes a nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Several alternatively spliced transcript variants of this gene have been described; however, the full-length nature of some of these variants has not been determined.^[6]