VAMP4

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Vesicle-associated membrane protein 4 is a protein that in humans is encoded by the VAMP4 gene.[5][6]

AliasesVAMP4, VAMP-4, VAMP24, vesicle associated membrane protein 4
End171,742,074 bp[1]
Quick facts Identifiers, Aliases ...
VAMP4
Identifiers
AliasesVAMP4, VAMP-4, VAMP24, vesicle associated membrane protein 4
External IDsOMIM: 606909; MGI: 1858730; HomoloGene: 37847; GeneCards: VAMP4; OMA:VAMP4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001185127
NM_003762
NM_201994

NM_016796
NM_001347125
NM_001356526
NM_001356527

RefSeq (protein)

NP_001172056
NP_003753

NP_001334054
NP_058076
NP_001343455
NP_001343456

Location (UCSC)Chr 1: 171.7 – 171.74 MbChr 1: 162.4 – 162.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport.[6]

Interactions

VAMP4 has been shown to interact with AP1M1,[7] STX6[8] and STX16.[8]

References

Further reading

Related Articles

Wikiwand AI