VPS37A

VPS37A
Identifiers
Aliases	VPS37A, HCRP1, PQBP2, SPG53, ESCRT-I subunit
External IDs	OMIM: 609927; MGI: 1261835; HomoloGene: 45120; GeneCards: VPS37A; OMA:VPS37A - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	17,302,427 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	40,551,134 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; gastrocnemius muscle; ; Achilles tendon; ; myocardium of left ventricle; ; right testis; ; tibialis anterior muscle; ; secondary oocyte; ; left testis; ; smooth muscle tissue; ; stromal cell of endometrium;
	Top expressed in
	muscle of thigh; ; spermatocyte; ; retinal pigment epithelium; ; supraoptic nucleus; ; substantia nigra; ; spermatid; ; vestibular membrane of cochlear duct; ; ascending aorta; ; neural layer of retina; ; aortic valve;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	endosome; centrosome; intracellular membrane-bounded organelle; late endosome membrane; membrane; nucleoplasm; endosome membrane; nucleus; cytosol; ESCRT I complex; host cell;
Biological process	viral budding via host ESCRT complex; viral life cycle; multivesicular body assembly; endosomal transport; protein transport; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; macroautophagy; endosome transport via multivesicular body sorting pathway; protein targeting to membrane; protein targeting to vacuole; intracellular transport of virus;
	Sources:Amigo / QuickGO
Orthologs
	137492
	52348
	ENSG00000155975
	ENSMUSG00000031600
	Q8NEZ2
	Q8CHS8
	NM_001145152; NM_152415
	NM_033560
NP_001138624; NP_689628; NP_001350096; NP_001350097; NP_001350098;
	NP_001350099; NP_001350100; NP_001350101; NP_001350102
	NP_291038
	Wikidata
View/Edit Human	View/Edit Mouse

Vacuolar protein sorting 37 homolog A (S. cerevisiae) is a protein in humans that is encoded by the VPS37A gene.^[5] It is a member of the endosomal sorting complex required for transport (ESCRT) system.^[6]