VTI1A

Vesicle transport through interaction with t-SNAREs homolog 1A is a protein that in humans is encoded by the VTI1A gene.^[5][6]

AliasesVTI1A, MMDS3, MVti1, VTI1RP2, Vti1-rp2, vesicle transport through interaction with t-SNAREs 1A

External IDsOMIM: 614316; MGI: 1855699; HomoloGene: 39963; GeneCards: VTI1A; OMA:VTI1A - orthologs

Chr.Chromosome 10 (human)^[1]

End112,818,744 bp^[1]

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VTI1A
Identifiers
Aliases	VTI1A, MMDS3, MVti1, VTI1RP2, Vti1-rp2, vesicle transport through interaction with t-SNAREs 1A
External IDs	OMIM: 614316; MGI: 1855699; HomoloGene: 39963; GeneCards: VTI1A; OMA:VTI1A - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q25.2 Start 112,446,998 bp[1] End 112,818,744 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 D2 Start 55,304,727 bp[2] End 55,615,741 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve Achilles tendon pancreatic ductal cell buccal mucosa cell testicle monocyte bone marrow cell corpus callosum epithelium of colon blood Top expressed in Rostral migratory stream granulocyte superior frontal gyrus right kidney genital tubercle dentate gyrus of hippocampal formation granule cell lumbar subsegment of spinal cord tail of embryo medial dorsal nucleus proximal tubule More reference expression data BioGPS n/a
Gene ontology Molecular function SNAP receptor activity protein binding SNARE binding Cellular component integral component of membrane endosome Golgi apparatus membrane synaptic vesicle autophagosome soma SNARE complex perinuclear region of cytoplasm neuron projection terminus cytoplasmic vesicle clathrin-coated vesicle trans-Golgi network membrane ER to Golgi transport vesicle membrane cytosol Golgi membrane late endosome membrane endoplasmic reticulum membrane intracellular membrane-bounded organelle Biological process voluntary musculoskeletal movement autophagy retrograde transport, endosome to Golgi protein transport intracellular protein transport Golgi ribbon formation vesicle-mediated transport Golgi to vacuole transport vesicle fusion with Golgi apparatus intra-Golgi vesicle-mediated transport endoplasmic reticulum to Golgi vesicle-mediated transport protein targeting to vacuole Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 143187 53611 Ensembl ENSG00000151532 ENSMUSG00000024983 UniProt Q96AJ9 O89116 RefSeq (mRNA) NM_145206 NM_001318203 NM_001318205 NM_001365710 NM_001365711 NM_001365712 NM_001365713 NM_001365714 NM_001293685 NM_001293686 NM_016862 NM_001360431 NM_001360432 RefSeq (protein) NP_001305132 NP_001305134 NP_660207 NP_001352639 NP_001352640 NP_001352641 NP_001352642 NP_001352643 NP_001280614 NP_001280615 NP_058558 NP_001347360 NP_001347361 Location (UCSC) Chr 10: 112.45 – 112.82 Mb Chr 19: 55.3 – 55.62 Mb PubMed search [3] [4]
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The protein encoded by the VTI1A gene is a vesicular-SNARE (v-SNARE) protein which is located in the membranes of target vesicle compartments.^[7]