Herpes simplex virus protein vmw65

Available protein structures:
PDB	16vp IPR003174 PF02232 (ECOD; PDBsum)
AlphaFold	IPR003174; PF02232;

Alpha trans-inducing protein (Alpha-TIF)
Alpha trans-inducing protein (Alpha-TIF)
	Structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16.
Identifiers
Symbol	Alpha_TIF
Pfam	PF02232
InterPro	IPR003174
SMART	SM00814
SCOP2	16vp / SCOPe / SUPFAM
PDB
Available protein structures:
PDB	16vp IPR003174 PF02232 (ECOD; PDBsum)
AlphaFold	IPR003174; PF02232;

Vmw65, also known as VP16 or α-TIF (Trans Inducing Factor)^[2] is a trans-acting protein that forms a complex with the host transcription factors Oct-1 and HCF to induce immediate early gene transcription in the herpes simplex viruses.^[3]^[4]

SymbolAlpha_TIF

Quick facts Alpha trans-inducing protein (Alpha-TIF), Identifiers ...

Close

VP16 is a strong transactivator^[5] and is often used in Y2H systems as the activation domain of the system.^[6]

References