WNK3

WNK3
Identifiers
Aliases	WNK3, PRKWNK lysine deficient protein kinase 3
External IDs	OMIM: 300358; MGI: 2652875; HomoloGene: 32493; GeneCards: WNK3; OMA:WNK3 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	54,358,642 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	150,103,148 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; buccal mucosa cell; ; tail of epididymis; ; testicle; ; gonad; ; caput epididymis; ; secondary oocyte; ; seminal vesicula; ; internal globus pallidus; ; retinal pigment epithelium;
	Top expressed in
	hand; ; lateral hypothalamus; ; lumbar subsegment of spinal cord; ; ventromedial nucleus; ; paraventricular nucleus of hypothalamus; ; dorsomedial hypothalamic nucleus; ; anterior amygdaloid area; ; tail of embryo; ; mammillary body; ; lateral septal nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; protein kinase activity; nucleotide binding; kinase activity; protein serine/threonine kinase activity; protein binding; chloride channel inhibitor activity; ATP binding; potassium channel inhibitor activity;
Cellular component	cytoplasm; bicellular tight junction; adherens junction; cytosol;
Biological process	phosphorylation; negative regulation of apoptotic process; protein phosphorylation; positive regulation of ion transmembrane transporter activity; positive regulation of peptidyl-threonine phosphorylation; positive regulation of sodium ion transport; protein autophosphorylation; positive regulation of sodium ion transmembrane transporter activity; negative regulation of pancreatic juice secretion; positive regulation of calcium ion transport; intracellular signal transduction; regulation of calcium ion import; protein localization to plasma membrane; positive regulation of protein localization to plasma membrane; ion homeostasis; negative regulation of sodium ion transport; positive regulation of potassium ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	65267
	279561
	ENSG00000196632
	ENSMUSG00000041245
	Q9BYP7
	Q80XP9
	NM_001002838; NM_020922; NM_001395166
	NM_001271678; NM_001271679
	NP_001002838; NP_065973
	NP_001258607; NP_001258608
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase WNK3, also known as protein kinase lysine-deficient 3, is a protein that in humans is encoded by the WNK3 gene.^[5]