WSB1

WD repeat and SOCS box-containing protein 1 is a protein that in humans is encoded by the WSB1 gene.^[5][6][7]

AliasesWSB1, SWIP1, WSB-1, WD repeat and SOCS box containing 1

External IDsOMIM: 610091; MGI: 1926139; HomoloGene: 9218; GeneCards: WSB1; OMA:WSB1 - orthologs

Chr.Chromosome 17 (human)^[1]

End27,315,926 bp^[1]

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WSB1
Identifiers
Aliases	WSB1, SWIP1, WSB-1, WD repeat and SOCS box containing 1
External IDs	OMIM: 610091; MGI: 1926139; HomoloGene: 9218; GeneCards: WSB1; OMA:WSB1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q11.1 Start 27,294,076 bp[1] End 27,315,926 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B5 Start 79,130,198 bp[2] End 79,145,497 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum gastric mucosa lower lobe of lung inferior ganglion of vagus nerve tibial nerve Region I of hippocampus proper tibial arteries canal of the cervix endothelial cell left uterine tube Top expressed in medullary collecting duct cumulus cell neural tube dorsomedial hypothalamic nucleus pineal gland vas deferens dermis paraventricular nucleus of hypothalamus ventral tegmental area Gonadal ridge More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding ubiquitin-protein transferase activity Cellular component intracellular anatomical structure cytosol Biological process protein ubiquitination intracellular signal transduction protein polyubiquitination post-translational protein modification biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26118 78889 Ensembl ENSG00000109046 ENSMUSG00000017677 UniProt Q9Y6I7 O54927 RefSeq (mRNA) NM_015626 NM_134264 NM_134265 NM_001348350 NM_001042565 NM_019653 RefSeq (protein) NP_056441 NP_599027 NP_001335279 NP_001036030 NP_062627 Location (UCSC) Chr 17: 27.29 – 27.32 Mb Chr 11: 79.13 – 79.15 Mb PubMed search [3] [4]
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This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.^[7]