Yimon Aye
American biochemist and molecular biologist
From Wikipedia, the free encyclopedia
Yimon Aye (Burmese: ရည်မွန်အေး; born 12 July 1980[1] in Burma) is an American chemist and molecular biologist. Currently she is a professor of chemistry & chemical biology at University of Oxford.[2]
Nucleotide signaling pathways
Associate professor Yimon Aye | |
|---|---|
ရည်မွန်အေး | |
Yimon Aye in 2018 | |
| Born | 12 July 1980 (age 45) |
| Citizenship | US-American |
| Known for | Electrophile signaling Nucleotide signaling pathways |
| Relatives | Soe Thein (father) |
| Academic background | |
| Education | Chemistry |
| Alma mater | University of Oxford Harvard University Massachusetts Institute of Technology |
| Doctoral advisor | David A. Evans |
| Other advisor | JoAnne Stubbe |
| Academic work | |
| Discipline | Biology |
| Sub-discipline | Molecular Biology |
| Institutions | University of Oxford |
| Main interests | Synthetic Methodology Chemical Biology Biochemistry Biophysics Molecular Biology Cell Biology |
| Website | https://www.chem.ox.ac.uk/people/yimon-aye |
Career
Aye spent her early life in Burma. She completed her undergraduate studies in chemistry at the University of Oxford and obtained her master's degree in 2004.[3] She joined Harvard University to study synthetic organic chemistry with David A. Evans, achieving her PhD in 2009.[4] She then moved to Massachusetts Institute of Technology as a Damon Runyon Cancer Research Foundation fellow to work with JoAnne Stubbe. There she performed research into the regulatory mechanisms of ribonucleotide reductase.[5]
In 2012, she started as an assistant professor at Cornell University, where she began her work on redox-dependent cell signaling and genome maintenance pathways. During this time, she developed REX technologies, new methods to facilitate the study of unconventional electrophile-regulated stress signaling paradigms.[6][7] REX technologies were one of the first approaches to forge direct links between upstream protein alteration by a reactive molecule and downstream responses.[4] From August 2018 to August 2024 she was an associate professor of chemistry at EPFL.[8]
Since September 2024 she's leading the Aye Lab at University of Oxford.[2] She is also a Professor of Chemistry and Chemical Biology. [9]In February 2026, the Aye Lab published a study, that demonstrates how generating small stressor metabolite can help a cell's ability to convert RNA messenger into proteins.[10]
Awards
Personal life
Yimon Aye's father Soe Thein is a former Commander-in-Chief of the Myanmar Navy.[17] She has a brother and a sister.[1]