ZNF10

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Zinc finger protein 10 is a protein that in humans is encoded by the ZNF10 gene.[3][4][5]

AliasesZNF10, KOX1, zinc finger protein 10
End133,159,465 bp[1]
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ZNF10
Identifiers
AliasesZNF10, KOX1, zinc finger protein 10
External IDsOMIM: 194538; HomoloGene: 130674; GeneCards: ZNF10; OMA:ZNF10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015394

n/a

RefSeq (protein)

NP_056209

n/a

Location (UCSC)Chr 12: 133.13 – 133.16 Mbn/a
PubMed search[2]n/a
Wikidata
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Function

The protein encoded by this gene contains a C2H2 zinc finger, and has been shown to function as a transcriptional repressor. The Kruppel-associated box (KRAB) domain of this protein is found to be responsible for its transcriptional repression activity. RING finger containing protein TIF1 was reported to interact with the KRAB domain, and may serve as a mediator for the repression activity of this protein.[5]

Interactions

ZNF10 has been shown to interact with TRIM28.[6][7]

References

Further reading

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