Wnt1

WNT1
Identifiants
Alias	WNT1
IDs externes	OMIM: 164820 MGI: 98953 HomoloGene: 3963 GeneCards: WNT1
Position du gène (humain)
Chr.	Chromosome 12 humain
Fin	48,982,620 bp
Position du gène (souris)
Chr.	Chromosome 15 (souris)
Fin	98,691,718 bp
Expression génique
	Fortement exprimé dans
	granulocyte; ; noyau accumbens; ; gyrus frontal supérieur; ; right frontal lobe; ; cortex préfrontal; ; putamen; ; sang; ; noyau caudé; ; moelle osseuse; ; Brodmann area 9;
	Fortement exprimé dans
	muscle layer of urethra; ; pelvic part of vagina; ; rhombic lip; ; canal éjaculateur; ; perineal part of vagina; ; masse cellulaire interne; ; epithelium of seminiferous tubule of testis; ; choroid plexus of fourth ventricle; ; female urethra; ; morula;
	Plus de données d'expression de référence
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	cytokine activity; protein domain specific binding; frizzled binding; morphogen activity; signaling receptor binding; receptor ligand activity;
Composant cellulaire	cytoplasme; endocytic vesicle membrane; endoplasmic reticulum lumen; membrane plasmique; région extracellulaire; surface cellulaire; Golgi lumen; exosome; milieu extracellulaire;
Processus biologique	negative regulation of cell-substrate adhesion; forebrain anterior/posterior pattern specification; dopaminergic neuron differentiation; neurogenèse; cell fate commitment; negative regulation of fat cell differentiation; positive regulation of protein phosphorylation; myotube differentiation; metencephalon development; midbrain-hindbrain boundary maturation during brain development; T cell differentiation in thymus; spinal cord association neuron differentiation; negative regulation of cell-cell adhesion; neuron fate determination; signal transduction in response to DNA damage; central nervous system morphogenesis; positive regulation of fibroblast proliferation; positive regulation of dermatome development; cell-cell signaling; negative regulation of cell differentiation; hematopoietic stem cell proliferation; cell proliferation in midbrain; positive regulation of DNA-binding transcription factor activity; embryonic axis specification; hepatocyte differentiation; negative regulation of transforming growth factor beta receptor signaling pathway; cerebellum development; ubiquitin-dependent SMAD protein catabolic process; cerebellum formation; negative regulation of BMP signaling pathway; canonical Wnt signaling pathway involved in negative regulation of apoptotic process; régulation positive de la transcription dépendante de l'ADN; développent d'un organisme multicellulaire; diencephalon development; branching involved in ureteric bud morphogenesis; cellular response to peptide hormone stimulus; midbrain-hindbrain boundary development; embryonic brain development; response to wounding; positive regulation of insulin-like growth factor receptor signaling pathway; inner ear morphogenesis; animal organ regeneration; positive regulation of cell population proliferation; negative regulation of ubiquitin-dependent protein catabolic process; neuron fate commitment; myoblast fusion; positive regulation of lamellipodium assembly; développement osseux; Spemann organizer formation; midbrain development; positive regulation of Notch signaling pathway; positive regulation of transcription by RNA polymerase II; Voie de signalisation Wnt; astrocyte-dopaminergic neuron signaling; positive regulation of canonical Wnt signaling pathway; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation; midbrain dopaminergic neuron differentiation; canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation; Wnt signaling pathway, planar cell polarity pathway; beta-catenin destruction complex disassembly; negative regulation of oxidative stress-induced neuron death; regulation of signaling receptor activity; canonical Wnt signaling pathway; negative regulation of apoptotic process; différenciation d'un neurone;
	Sources:Amigo / QuickGO
Orthologues
	7471
	22408
	ENSG00000125084
	ENSMUSG00000022997
	P04628
	P04426
	NM_005430
	NM_021279
	NP_005421
	NP_067254
	Wikidata
Voir/Editer Humain	Voir/Editer Souris