GSK-3β

GSK3B
PDBに登録されている構造
PDB	オルソログ検索: RCSB PDBe PDBj
PDBのIDコード一覧
	1GNG, 1H8F, 1I09, 1J1B, 1J1C, 1O6K, 1O6L, 1O9U, 1PYX, 1Q3D, 1Q3W, 1Q41, 1Q4L, 1Q5K, 1R0E, 1UV5, 2JDO, 2JDR, 2JLD, 2O5K, 2OW3, 2UW9, 2X39, 2XH5, 3CQU, 3CQW, 3DU8, 3E87, 3E88, 3E8D, 3F7Z, 3F88, 3GB2, 3I4B, 3L1S, 3M1S, 3MV5, 3OW4, 3PUP, 3Q3B, 3QKK, 3SAY, 3SD0, 3ZDI, 3ZRK, 3ZRL, 3ZRM, 4ACC, 4ACD, 4ACG, 4ACH, 4AFJ, 4B7T, 4DIT, 4EKK, 4IQ6, 4J1R, 4J71, 4NM0, 4NM3, 4NM5, 4NM7, 4PTC, 4PTE, 4PTG, 5F94, 5F95, 5HLP, 5HLN
識別子
記号	GSK3B, Gsk3b, 7330414F15Rik, 8430431H08Rik, C86142, GSK-3, GSK-3beta, GSK3, glycogen synthase kinase 3 beta
外部ID	OMIM: 605004 MGI: 1861437 HomoloGene: 55629 GeneCards: GSK3B
EC番号	2.7.11.1
遺伝子の位置 (ヒト)
染色体	3番染色体 (ヒト)
終点	120,094,994 bp
遺伝子の位置 (マウス)
染色体	16番染色体 (マウス)
終点	38,066,446 bp
RNA発現パターン
	さらなる参照発現データ
遺伝子オントロジー
分子機能	• キナーゼ活性; • ATP binding; • protein kinase activity; • protein kinase A catalytic subunit binding; • protein serine/threonine kinase activity; • トランスフェラーゼ活性; • NF-kappaB binding; • tau-protein kinase activity; • 血漿タンパク結合; • ヌクレオチド結合; • p53結合; • ubiquitin protein ligase binding; • protease binding; • beta-catenin binding; • プロテインキナーゼ結合; • dynactin binding; • tau protein binding;
細胞の構成要素	• 細胞質; • 膜; • ミトコンドリア; • 細胞核; • 中心体; • 細胞膜; • 細胞質基質; • beta-catenin destruction complex; • postsynapse; • Wnt signalosome; • 核質; • 神経繊維; • 樹状突起; • glutamatergic synapse;
生物学的プロセス	• 周期的プロセス; • negative regulation of type B pancreatic cell development; • negative regulation of protein binding; • negative regulation of glycogen (starch) synthase activity; • glycogen metabolic process; • 上側頭回発生; • negative regulation of canonical Wnt signaling pathway; • chemical synaptic transmission, postsynaptic; • negative regulation of protein-containing complex assembly; • positive regulation of protein export from nucleus; • positive regulation of GTPase activity; • 自己リン酸化; • 細胞分化; • negative regulation of protein localization to nucleus; • リン酸化; • positive regulation of cell-matrix adhesion; • 神経系発生; • dopamine receptor signaling pathway; • 上皮間葉転換; • peptidyl-threonine phosphorylation; • positive regulation of protein-containing complex assembly; • positive regulation of neuron death; • negative regulation of glycogen biosynthetic process; • 多細胞個体の発生; • regulation of cellular response to heat; • negative regulation of signal transduction; • 海馬発生; • beta-catenin destruction complex disassembly; • proteasome-mediated ubiquitin-dependent protein catabolic process; • Wntシグナル経路; • beta-catenin destruction complex assembly; • タンパク質リン酸化; • positive regulation of mitochondrion organization; • intracellular signal transduction; • positive regulation of protein catabolic process; • negative regulation of dopaminergic neuron differentiation; • ER overload response; • 概日リズム; • peptidyl-serine phosphorylation; • positive regulation of protein binding; • positive regulation of proteasomal ubiquitin-dependent protein catabolic process; • regulation of microtubule-based process; • cellular response to interleukin-3; • negative regulation of apoptotic process; • canonical Wnt signaling pathway; • extrinsic apoptotic signaling pathway in absence of ligand; • positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; • 炭水化物代謝; • neuron projection development; • negative regulation of neuron death; • positive regulation of gene expression; • establishment of cell polarity; • maintenance of cell polarity; • regulation of axon extension; • negative regulation of phosphoprotein phosphatase activity; • regulation of dendrite morphogenesis; • regulation of axonogenesis; • 興奮性シナプス後電位; • regulation of microtubule cytoskeleton organization; • negative regulation of calcineurin-NFAT signaling cascade; • extrinsic apoptotic signaling pathway; • neuron projection retraction; • negative regulation of protein acetylation; • cellular response to amyloid-beta; • positive regulation of protein localization to centrosome; • regulation of synaptic vesicle exocytosis; • neuron projection organization; • positive regulation of autophagy; • regulation of circadian rhythm; • regulation of long-term synaptic potentiation; • regulation of microtubule anchoring at centrosome;
	出典:Amigo / QuickGO
オルソログ
	2932
	56637
	ENSG00000082701
	ENSMUSG00000022812
	P49841
	Q9WV60
	NM_001146156; NM_002093; NM_001354596
	NM_019827; NM_001347232
	NP_001139628; NP_002084; NP_001341525
	NP_001334161; NP_062801
	ウィキデータ
閲覧/編集ヒト	閲覧/編集マウス