TNF受容体1型

TNFRSF1A
PDBに登録されている構造
PDB	オルソログ検索: RCSB PDBe PDBj
PDBのIDコード一覧
	1EXT, 1FT4, 1ICH, 1NCF, 1TNR
識別子
記号	TNFRSF1A, CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60, tumor necrosis factor receptor superfamily member 1A, TNF receptor superfamily member 1A
外部ID	OMIM: 191190 MGI: 1314884 HomoloGene: 828 GeneCards: TNFRSF1A
遺伝子の位置 (ヒト)
染色体	12番染色体 (ヒト)
終点	6,342,114 bp
遺伝子の位置 (マウス)
染色体	6番染色体 (マウス)
終点	125,339,447 bp
RNA発現パターン
	さらなる参照発現データ
遺伝子オントロジー
分子機能	• 血漿タンパク結合; • tumor necrosis factor-activated receptor activity; • tumor necrosis factor binding; • identical protein binding;
細胞の構成要素	• integral component of membrane; • ゴルジ体; • 膜; • ゴルジ膜; • receptor complex; • 細胞膜; • integral component of plasma membrane; • 細胞外領域; • cell surface; • ミトコンドリア; • 脂質ラフト; • 細胞外空間; • tumor necrosis factor receptor superfamily complex;
生物学的プロセス	• regulation of apoptotic process; • prostaglandin metabolic process; • 防衛反応; • positive regulation of ceramide biosynthetic process; • positive regulation of inflammatory response; • regulation of tumor necrosis factor-mediated signaling pathway; • tumor necrosis factor-mediated signaling pathway; • リポ多糖への反応; • cellular response to mechanical stimulus; • death-inducing signaling complex assembly; • regulation of cell population proliferation; • defense response to bacterium; • 免疫応答; • intrinsic apoptotic signaling pathway in response to DNA damage; • positive regulation of I-kappaB kinase/NF-kappaB signaling; • viral process; • I-kappaB kinase/NF-kappaB signaling; • negative regulation of inflammatory response; • regulation of establishment of endothelial barrier; • extrinsic apoptotic signaling pathway via death domain receptors; • positive regulation of transcription by RNA polymerase II; • シグナル伝達; • アポトーシス; • 炎症反応; • 細胞表面受容体シグナル伝達経路; • positive regulation of tyrosine phosphorylation of STAT protein; • protein localization to plasma membrane; • サイトカイン媒介シグナル伝達経路; • 大動脈弁発生; • 肺動脈弁発生; • negative regulation of extracellular matrix constituent secretion; • negative regulation of cardiac muscle hypertrophy; • positive regulation of apoptotic process involved in morphogenesis;
	出典:Amigo / QuickGO
オルソログ
	7132
	21937
	ENSG00000067182
	ENSMUSG00000030341
	P19438,F5H8A6
	P25118
	NM_001065; NM_001346091; NM_001346092
	NM_011609
	NP_001056; NP_001333020; NP_001333021
	NP_035739
	ウィキデータ
閲覧/編集ヒト	閲覧/編集マウス

TNF受容体1型（1型TNF受容体、tumor necrosis factor receptor 1、TNFR1）、TNFRSF1A（tumor necrosis factor receptor superfamily, member 1A）またはCD120aはTNF-αを結合する膜受容体であり、普遍的に発現している^[5]^[6]^[7]。

PDBオルソログ検索: RCSB PDBe PDBj

記号TNFRSF1A, CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60, tumor necrosis factor receptor superfamily member 1A, TNF receptor superfamily member 1A

外部IDOMIM: 191190 MGI: 1314884 HomoloGene: 828 GeneCards: TNFRSF1A

染色体12番染色体 (ヒト)^[1]

概要 TNFRSF1A, PDBに登録されている構造 ...

閉じる

[5]

[6]

[7]

[1]

[2]

[3]

[4]

TNF受容体1型

機能

臨床的意義

相互作用

出典

関連文献

関連項目

外部リンク

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