Methoxyphenamine

Pair of enantiomers From Wikipedia, the free encyclopedia

Methoxyphenamine (trade names ASMI, Euspirol, Orthoxine, Ortodrinex, Proasma), also known as 2-methoxy-N-methylamphetamine (OMMA), is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator.[1]

AHFS/Drugs.comInternational Drug Names
Routes of
administrationOral
ATC code
Legal status
  • In general: ℞ (Prescription only)
Quick facts Clinical data, AHFS/Drugs.com ...
Methoxyphenamine
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
MetabolismO-demethylation
MetabolitesODMP
Identifiers
  • 1-(2-methoxyphenyl)-N-methylpropan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.002.035 Edit this at Wikidata
Chemical and physical data
FormulaC11H17NO
Molar mass179.263 g·mol−1
3D model (JSmol)
  • CC(CC1=CC=CC=C1OC)NC
  • InChI=1S/C11H17NO/c1-9(12-2)8-10-6-4-5-7-11(10)13-3/h4-7,9,12H,8H2,1-3H3
  • Key:OEHAYUOVELTAPG-UHFFFAOYSA-N
Close

It acts as an anti-inflammatory in rats.[2]

Chemistry

Methoxyphenamine was first synthesized at the Upjohn company by Woodruff and co-workers.[3] A later synthesis by Heinzelman, from the same company, corrects the melting point given for methoxyphenamine hydrochloride in the earlier paper, and describes an improved synthetic procedure, as well as resolution of the racemic methoxyphenamine.[4]

See also

References

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