2022 Challenger Biel/Bienne

Country	Player	Rank1	Seed
FRA	Pierre-Hugues Herbert	111	1
AUT	Dennis Novak	140	2
SUI	Dominic Stricker	155	3
TUR	Altuğ Çelikbilek	162	4
	Pavel Kotov	168	5
GER	Daniel Masur	176	6
SUI	Marc-Andrea Hüsler	179	7
NED	Tim van Rijthoven	180	8

• ¹ Rankings are as of 14 March 2022.^[1]

The following players received wildcards into the singles main draw:

• Kilian Feldbausch
• Jérôme Kym
• Leandro Riedi

The following players received entry into the singles main draw using protected rankings:

• Li Zhe
• Go Soeda

The following players received entry from the qualifying draw:

• Gijs Brouwer
• Marek Gengel
• Aleksandar Kovacevic
• Georgii Kravchenko
• Jelle Sels
• Otto Virtanen

The following players received entry as lucky losers:

• Adrián Menéndez Maceiras
• Aldin Šetkić

• Jurij Rodionov def. Kacper Żuk 7–6^(7–3), 6–4.

• Pierre-Hugues Herbert / Albano Olivetti def. Purav Raja / Ramkumar Ramanathan 6–3, 6–4.