2CE-5-EtO
Pharmaceutical compound
From Wikipedia, the free encyclopedia
2CE-5-EtO, also known as 4-ethyl-2-methoxy-5-ethoxyphenethylamine or as Eternity, is a psychoactive drug of the phenethylamine, 2C, and TWEETIO families related to the psychedelic drug 2C-E.[1][2][3] It is the derivative of 2C-E in which the methoxy group at the 5 position has been replaced with an ethoxy group.[1][2][3]
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| Clinical data | |
|---|---|
| Other names | 2CE-5EtO; 2CE-5-ETO; 2CE-5ETO; 2-Methoxy-4-ethyl-5-ethoxyphenethylamine; 4-Ethyl-2-methoxy-5-ethoxyphenethylamine; Eternity |
| Routes of administration | Oral[1][2][3] |
| Drug class | Psychoactive drug |
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| Pharmacokinetic data | |
| Onset of action | 3–4 hours (plateau)[1] |
| Duration of action | 16–24 hours[1][2][3] |
| Identifiers | |
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| Chemical and physical data | |
| Formula | C13H21NO2 |
| Molar mass | 223.316 g·mol−1 |
| 3D model (JSmol) | |
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According to Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, 2CE-5-EtO's dose is 10 to 15 mg orally and its duration is 16 to 24 hours.[1][2][3] It has a slow onset of 3 to 4 hours to reach a plateau of effects and is described as extremely long-lived, with a duration 2 to 3 times longer than that of 2C-E.[1][2] The drug is said to be gentle and forgiving, but its effects were not otherwise described.[1] Due to its very long duration, it has sometimes been counteracted with a benzodiazepine like diazepam or triazolam at the 16-hour point to allow sleep, but with effects still evident the next day.[1] One subject gave it the nickname "Eternity".[1]
The chemical synthesis of 2CE-5-EtO has been described.[1]
2CE-5-EtO was first described in the literature by Shulgin in PiHKAL in 1991.[1] It was developed and tested by Darrell Lemaire, with publication via personal communication with Shulgin.[2][4][5][6][7] The drug is a controlled substance in Canada under phenethylamine blanket-ban language.[8]