2CE-5-EtO

Pharmaceutical compound From Wikipedia, the free encyclopedia

2CE-5-EtO, also known as 4-ethyl-2-methoxy-5-ethoxyphenethylamine or as Eternity, is a psychoactive drug of the phenethylamine, 2C, and TWEETIO families related to the psychedelic drug 2C-E.[1][2][3] It is the derivative of 2C-E in which the methoxy group at the 5 position has been replaced with an ethoxy group.[1][2][3]

Other names2CE-5EtO; 2CE-5-ETO; 2CE-5ETO; 2-Methoxy-4-ethyl-5-ethoxyphenethylamine; 4-Ethyl-2-methoxy-5-ethoxyphenethylamine; Eternity
ATC code
  • None
Quick facts Clinical data, Other names ...
2CE-5-EtO
Clinical data
Other names2CE-5EtO; 2CE-5-ETO; 2CE-5ETO; 2-Methoxy-4-ethyl-5-ethoxyphenethylamine; 4-Ethyl-2-methoxy-5-ethoxyphenethylamine; Eternity
Routes of
administration
Oral[1][2][3]
Drug classPsychoactive drug
ATC code
  • None
Pharmacokinetic data
Onset of action3–4 hours (plateau)[1]
Duration of action16–24 hours[1][2][3]
Identifiers
  • 2-(5-ethoxy-4-ethyl-2-methoxyphenyl)ethan-1-amine
Chemical and physical data
FormulaC13H21NO2
Molar mass223.316 g·mol−1
3D model (JSmol)
  • CCC(C(OCC)=C1)=CC(OC)=C1CCN
  • InChI=1S/C13H21NO2/c1-4-10-8-12(15-3)11(6-7-14)9-13(10)16-5-2/h8-9H,4-7,14H2,1-3H3
  • Key:DDGVPHDBSPJOPN-UHFFFAOYSA-N
Close

According to Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, 2CE-5-EtO's dose is 10 to 15 mg orally and its duration is 16 to 24 hours.[1][2][3] It has a slow onset of 3 to 4 hours to reach a plateau of effects and is described as extremely long-lived, with a duration 2 to 3 times longer than that of 2C-E.[1][2] The drug is said to be gentle and forgiving, but its effects were not otherwise described.[1] Due to its very long duration, it has sometimes been counteracted with a benzodiazepine like diazepam or triazolam at the 16-hour point to allow sleep, but with effects still evident the next day.[1] One subject gave it the nickname "Eternity".[1]

The chemical synthesis of 2CE-5-EtO has been described.[1]

2CE-5-EtO was first described in the literature by Shulgin in PiHKAL in 1991.[1] It was developed and tested by Darrell Lemaire, with publication via personal communication with Shulgin.[2][4][5][6][7] The drug is a controlled substance in Canada under phenethylamine blanket-ban language.[8]

See also

References

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