![](#/media/File:3"-deamino-3"'-oxonicotianamine.svg)
3''-deamino-3''-oxonicotianamine reductase
Class of enzymes
From Wikipedia, the free encyclopedia
3''-deamino-3''-oxonicotianamine reductase (EC 1.1.1.285) is an enzyme that catalyzes the chemical reaction
| 3″-deamino-3″-oxonicotianamine reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.285 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The three substrates of this enzyme are 3''-deamino-3''-oxonicotianamine, reduced nicotinamide adenine dinucleotide (NADH), and a proton. Its products are 2'-deoxymugineic acid and oxidised (NAD+). This enzyme can also use the alternative cofactor, nicotinamide adenine dinucleotide phosphate.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-deoxymugineic acid:NAD(P)+ 3-oxidoreductase. It is part of the pathway which converts the siderophore, nicotianamine, to other metal-chelating molecules in higher plants. These allow the plant to efficiently take up metals such as zinc and iron from the soil.[3]
