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4'-Methyl-α-pyrrolidinohexiophenone

Chemical compound From Wikipedia, the free encyclopedia

4'-Methyl-α-pyrrolidinohexiophenone (MPHP) is a stimulant compound which has been reported as a novel designer drug.[1][2][3] It is closely related to pyrovalerone, being simply its chain-lengthened homologue. In the pyrrolidinophenone series, stimulant activity is maintained so long as the positions of the aryl, ketone and pyrrolidinyl groups are held constant, while the alkyl backbone can be varied anywhere between three and as many as seven carbons,[4] with highest potency usually seen with the pentyl or isohexyl backbone, and a variety of substituents are tolerated on the aromatic ring.[5]

Other namesMPHP
Legal status
Quick facts Clinical data, Other names ...
4'-Methyl-α-pyrrolidinohexiophenone
Clinical data
Other namesMPHP
Legal status
Legal status
Identifiers
  • (RS)-1-(4-Methylphenyl)-2-(1-pyrrolidinyl)-1-hexanone
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H25NO
Molar mass259.393 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • c2cc(C)ccc2C(=O)C(CCCC)N1CCCC1
  • InChI=1S/C17H25NO/c1-3-4-7-16(18-12-5-6-13-18)17(19)15-10-8-14(2)9-11-15/h8-11,16H,3-7,12-13H2,1-2H3
  • Key:YOSQVMGMENUCDX-UHFFFAOYSA-N
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In 2010 a group of researchers from the Institute of Forensic Medicine, University Hospital Jena, Germany concluded that MPHP can lead to serious poisoning with toxic liver damage and rhabdomyolysis.[6]

Legality

In the United States, MPHP is a Schedule I Controlled Substance.[7] Sweden's public health agency suggested to classify MPHP as narcotic on June 1, 2015.[8]

See also

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