4,4'-Diapophytoene desaturase
Enzyme
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4,4'-Diapophytoene desaturase (EC 1.3.8.2, dehydrosqualene desaturase, CrtN, 4,4'-diapophytoene:FAD oxidoreductase) is an enzyme with systematic name 15-cis-4,4'-diapophytoene:FAD oxidoreductase.[1][2][3] This enzyme catalyses the following chemical reaction
- 15-cis-4,4'-diapophytoene + 4 FAD all-trans-4,4'-diapolycopene + 4 FADH2 (overall reaction)
- (1a) 15-cis-4,4'-diapophytoene + FAD all-trans-4,4'-diapophytofluene + FADH2
- (1b) all-trans-4,4'-diapophytofluene + FAD all-trans-4,4'-diapo-zeta-carotene + FADH2
- (1c) all-trans-4,4'-diapo-zeta-carotene + FAD all-trans-4,4'-diaponeurosporene + FADH2
- (1d) all-trans-4,4'-diaponeurosporene + FAD all-trans-4,4'-diapolycopene + FADH2
| 4,4'-diapophytoene desaturase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.8.2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is typical of Staphylococcus aureus and some other bacteria such as Heliobacillus sp.