Para-Bromoamphetamine
Chemical compound
From Wikipedia, the free encyclopedia
para-Bromoamphetamine (PBA), also known as 4-bromoamphetamine (4-BA), is an amphetamine derivative which acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) and produces stimulant effects.
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| Formula | C9H12BrN |
| Molar mass | 214.106 g·mol−1 |
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Another related compound is para-bromomethamphetamine (PBMA) known by the codename V-111.[1]
Pharmacology
PBA has been found to be a monoamine oxidase A (MAO-A) inhibitor, with an IC50 of 1,500 nM.[2]
Neurotoxicity
Like most other para-substituted amphetamines, PBA can be neurotoxic and may deplete the brain of 5-hydroxyindoles for at least a week.[3]
6-BAT
Given that 6-CAT is a non-neurotoxic version of para-chloroamphetamine, it is worth considering 6-BAT as well.
The chemical name for this is 6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine or 6-bromo-2-aminotetralin [167355-41-1] [867-970-2]. The synthesis method is disclosed (Ex 32).[4][5] The precursor is called 6-Bromo-2-tetralone [4133-35-1] [640-168-8] (Ex 16).[6]
See also
- Substituted amphetamines
- 4-Bromomethcathinone (4-BMC)
- 4-Fluoroamphetamine (4-FA)
- para-Chloroamphetamine (PCA)
- para-Iodoamphetamine (PIA)
- para-Bromomethamphetamine (PBMA)