ABI gene family member 3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

ABI gene family member 3 (ABI3) also known as new molecule including SH3 (Nesh) is a protein that in humans is encoded by the ABI3 gene.[5][6][7]

AliasesABI3, NESH, SSH3BP3, ABI family member 3
End49,223,225 bp[1]
Quick facts ABI3, Identifiers ...
ABI3
Identifiers
AliasesABI3, NESH, SSH3BP3, ABI family member 3
External IDsOMIM: 606363; MGI: 1913860; HomoloGene: 9505; GeneCards: ABI3; OMA:ABI3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001135186
NM_016428

NM_001163464
NM_025659

RefSeq (protein)

NP_001128658
NP_057512

NP_001156936
NP_079935

Location (UCSC)Chr 17: 49.21 – 49.22 MbChr 11: 95.72 – 95.73 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinases.[7]

See also

References

Further reading

Related Articles

Wikiwand AI