Aldehyde oxidase 1

AOX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UHW, 4UHX, 5EPG
Identifiers
Aliases	AOX1, AO, AOH1, aldehyde oxidase 1
External IDs	OMIM: 602841; MGI: 88035; HomoloGene: 68165; GeneCards: AOX1; OMA:AOX1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	200,677,064 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	58,145,572 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; left adrenal cortex; ; right lobe of liver; ; body of pancreas; ; left uterine tube; ; germinal epithelium; ; subcutaneous adipose tissue; ; right ovary; ; kidney tubule; ; gastric mucosa;
	Top expressed in
	left lobe of liver; ; tunica adventitia of aorta; ; lumbar spinal ganglion; ; brown adipose tissue; ; soleus muscle; ; tunica media of zone of aorta; ; white adipose tissue; ; facial motor nucleus; ; esophagus; ; intercostal muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	oxidoreductase activity, acting on CH-OH group of donors; iron-sulfur cluster binding; NAD binding; metal ion binding; catalytic activity; electron transfer activity; oxidoreductase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors; aldehyde oxidase activity; iron ion binding; protein homodimerization activity; molybdopterin cofactor binding; flavin adenine dinucleotide binding; 2 iron, 2 sulfur cluster binding; identical protein binding; xanthine dehydrogenase activity; FAD binding;
Cellular component	extracellular exosome; cytoplasm; cytosol; nuclear body;
Biological process	xanthine catabolic process; vitamin B6 metabolic process; electron transport chain;
	Sources:Amigo / QuickGO
Orthologs
	316
	11761
	ENSG00000138356
	ENSMUSG00000063558
	Q06278
	O54754
	NM_001159
	NM_009676
	NP_001150
	NP_033806
	Wikidata
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