Adapalene/benzoyl peroxide
Pharmaceutical combination
From Wikipedia, the free encyclopedia
Adapalene/benzoyl peroxide, sold under the brand name Epiduo among others, is a fixed-dose combination medication for the treatment of acne vulgaris.[2][3] It is a combination of adapalene, a synthetic retinoid; and benzoyl peroxide, an oxidizing agent.[2][3]
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| Combination of | |
|---|---|
| Adapalene | Retinoid |
| Benzoyl peroxide | Oxidizing agent |
| Clinical data | |
| Trade names | Epiduo Gel, Epiduo Forte, others |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| License data | |
| Routes of administration | Topical |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| KEGG | |
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Adapalene/benzoyl peroxide (Epiduo Gel) was approved for medical use in the United States in December 2008.[5] Adapalene/benzoyl peroxide (Epiduo Forte) with a stronger adapalene strength was approved for medical use in the United States in July 2015.[6] Adapalene/benzoyl peroxide (Differin Epiduo Acne Gel) is an over-the-counter version of Epiduo Gel that was approved for medical use in the United States in May 2026.[7][8]
It is available as a generic medication.[9] In 2023, it was the 319th most commonly prescribed medication in the United States, with more than 200,000 prescriptions.[10]
Medical uses
Adapalene/benzoyl peroxide is indicated for the topical treatment of acne vulgaris.[2][3]
