Chanturia returned to Georgia permanently in 1920, and settled in Senaki with his wife, an Englishwoman named Kate Walter Ball, whom he taught Georgian and Mingrelian. He often travelled to Tbilisi to work at the newly established Tbilisi State University, and at various museums and libraries. He declined an offer to work for the Ministry of Foreign Affairs, as his main goal was now the establishment of a museum in Samegrelo.
This museum opened on 1 May 1921 in the Dadiani Palace in Zugdidi. Objects from the other mansions of the Dadiani family, and of the private collection of Prince Achille Murat-Dadiani, were transferred to the newly created museum.
From 1937, Chanturia was persecuted by the Soviet authorities. In 1940, he was dismissed from the museum he had created. He died in Zugdidi on May 11, 1949.