Aloe emodin

Aloe emodin (1,8-dihydroxy-3-(hydroxymethyl)anthraquinone) is an anthraquinone and an isomer of emodin present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action.^[1] Aloe emodin is not carcinogenic when applied to the skin, although it may increase the carcinogenicity of some kinds of radiation.^[2][3]

Other namesRhabarberone

Routes of
administrationOral

ATC code

• None

CAS Number

• 481-72-1 ^N

Quick facts Clinical data, Other names ...

Aloe emodin

Clinical data
Other names	Rhabarberone
Routes of administration	Oral
ATC code	None
Identifiers
IUPAC name 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione
CAS Number	481-72-1 N
PubChem CID	10207
ChemSpider	9792 Y
UNII	C8IYT9CR7C
KEGG	C10294 Y
ChEBI	CHEBI:2607 N
ChEMBL	ChEMBL40275 Y
CompTox Dashboard (EPA)	DTXSID2030695
ECHA InfoCard	100.006.884
Chemical and physical data
Formula	C15H10O5
Molar mass	270.240 g·mol−1
3D model (JSmol)	Interactive image
Melting point	223 to 224 °C (433 to 435 °F) Sublimes in CO2 stream
SMILES O=C2c1cccc(O)c1C(=O)c3c2cc(cc3O)CO
InChI InChI=1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2 Y Key:YDQWDHRMZQUTBA-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

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Aloe emodin is found in the gel, sap or leaves of aloe vera, the socotrine aloe, and Zanzibar aloes, the bark of Frangula (Rhamnus frangula) and cascara sagrada (Rhamnus purshiana), the leaves of Senna (Cassia angustifolia), and the rhizome of rhubarb (Rheum rhaponticum).^{[citation needed]} Aloe-emodin has not been found in Natal aloes.^{[citation needed]}