Motexafin lutetium
Chemical compound
From Wikipedia, the free encyclopedia
Motexafin lutetium is a texaphyrin, marketed as Antrin by Pharmacyclics Inc.
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| Other names
Antrin; Lu texaphyrin; Lu-Tex; Lutetium texaphyrin; Lutrin; Optrin; PCI 0123 | |
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3D model (JSmol) |
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| Properties | |
| C52H72LuN5O14 | |
| Molar mass | 1166.136 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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It is a photosensitiser for use in photodynamic therapy to treat skin conditions and superficial cancers.
It has also been tested for use in photoangioplasty (photodynamic treatment of diseased arteries).[1]
It is photoactivated by 732 nm light which allows greater depth of penetration.[2]
Clinical trials
Phase II clinical trials were in progress in 1999.[3]
A phase I trial for prostate cancer reported in 2009.[4]
