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Butyrophilin, subfamily 2, member A2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Butyrophilin subfamily 2 member A2 is a protein that in humans is encoded by the BTN2A2 gene.[5][6][7]

AliasesBTN2A2, BT2.2, BTF2, BTN2.2, Butyrophilin, subfamily 2, member A2, butyrophilin subfamily 2 member A2
End26,394,874 bp[1]
Quick facts BTN2A2, Identifiers ...
BTN2A2
Identifiers
AliasesBTN2A2, BT2.2, BTF2, BTN2.2, Butyrophilin, subfamily 2, member A2, butyrophilin subfamily 2 member A2
External IDsOMIM: 613591; MGI: 3606486; GeneCards: BTN2A2
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001289614
NM_001289615
NM_175938

RefSeq (protein)

NP_001276543
NP_001276544
NP_787952

Location (UCSC)Chr 6: 26.38 – 26.39 MbChr 13: 23.66 – 23.67 Mb
PubMed search[3][4]
Wikidata
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Function

Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type 1 receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.[7]

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