Etoxeridine

Etoxeridine (Carbetidine, Atenos) is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine).

Other namesEtoxeridine, Carbetidine, Atenos

ATC code

• none

Legal status

• AU: S9 (Prohibited substance)
• BR: Class A1 (Narcotic drugs)^[1]
• CA: Schedule I
• DE: Anlage I (Authorized scientific use only)
• UK: Class A
• US: Schedule I

CAS Number

• 469-82-9 ^Y

Quick facts Clinical data, Other names ...

Etoxeridine

Clinical data
Other names	Etoxeridine, Carbetidine, Atenos
ATC code	none
Legal status
Legal status	AU: S9 (Prohibited substance) BR: Class A1 (Narcotic drugs)[1] CA: Schedule I DE: Anlage I (Authorized scientific use only) UK: Class A US: Schedule I
Identifiers
IUPAC name Ethyl 1-[2-(2-hydroxyethoxy)ethyl]-4-phenylpiperidine-4-carboxylate
CAS Number	469-82-9 Y
PubChem CID	61122
DrugBank	DB01505 Y
ChemSpider	55070 Y
UNII	RHW35E1G7E
KEGG	D12680 Y
ChEMBL	ChEMBL2104254
CompTox Dashboard (EPA)	DTXSID30196980
ECHA InfoCard	100.006.750
Chemical and physical data
Formula	C18H27NO4
Molar mass	321.417 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1(CCN(CC1)CCOCCO)(C(=O)OCC)C2=CC=CC=C2
InChI InChI=1S/C18H27NO4/c1-2-23-17(21)18(16-6-4-3-5-7-16)8-10-19(11-9-18)12-14-22-15-13-20/h3-7,20H,2,8-15H2,1H3 Y Key:KJTKYGFGPQSRRA-UHFFFAOYSA-N Y
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Etoxeridine was developed in the 1950s^[2] and investigated for use in surgical anesthesia, however it was never commercialized and is not currently used in medicine.^[3][4][5] As with other opioids which were not in clinical use during the drafting of the Controlled Substances Act, it is categorized as a Schedule I narcotic.